Structure of PDB 6imk Chain A Binding Site BS03

Receptor Information
>6imk Chain A (length=409) Species: 10497 (African swine fever virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMLNQFPGQYSNNIFCFPPIESETKSGKKASWIICVQVVQHNTIIPITDE
MFSTDVKDAVAEIFTKFFVEEGAVRISKMTRVTEGKNLGKKNATTVVHQA
FKDALSKYNRHARQKRGNRGMIPPMLVKYFNIIPKTFFEEETDPIVQRKR
NGVRAVACQQGDGCILLYSRTEKEFLGLDNIKKELKQLYLFIDVRVYLDG
ELYLHRKPLQWIAGQANAKTDSSELHFYVFDCFWSDQLQMPSNKRQQLLT
NIFKQKEDLTFIHQVENFSVKNVDEALRLKAQFIKEGYEGAIVRNANGPY
EPGYNNYHSAHLAKLKPLLDAEFILVDYTQGKKGKDLGAILWVCELPNKK
RFVVTPKHLTYADRYALFQKLTPALFKKHLYGKELTVEYAELSPKTGIPL
QARAVGFRE
Ligand information
Receptor-Ligand Complex Structure
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PDB6imk Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues.
Resolution2.502 Å
Binding residue
(original residue number in PDB)		S25 K27 G71 A72 R74 K359 H360 T362 Y363 R405
Binding residue
(residue number reindexed from 1)		S26 K28 G72 A73 R75 K357 H358 T360 Y361 R403
Enzymatic activity
Enzyme Commision number 6.5.1.1: DNA ligase (ATP).
Gene Ontology
Molecular Function
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0051301 cell division
Cellular Component
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6imk, PDBe:6imk, PDBj:6imk
PDBsum6imk
PubMed30674878
UniProtP35970|DNLI_ASFB7 DNA ligase (Gene Name=LIG)

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