Structure of PDB 6iht Chain A Binding Site BS03

Receptor Information

>6iht Chain A (length=243) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HMEAQFFTDTGQHRDKNEDAGGIFYNQTNQQLLVLCDGMGGHKAGEVASK
FVTDELKSRFEAENLIEQHQAENWLRNNIKDINFQLYHYAQENAEYKGMG
TTCVCALVFEKSVVIANVGDSRAYVINSRQIEQITSDHSFVNHLVLTGQI
TPEEAFTHPQRNIITKVMGTDKRVSPDLFIKRLNFYDYLLLNSDGLTDYV
KDNEIKRLLVKEGTIEDHGDQLMQLALDNHSKDNVTFILAAIE

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

6iht Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6iht Structural Insight into the Mechanism of Staphylococcus aureus Stp1 Phosphatase.
Resolution	1.569 Å
Binding residue (original residue number in PDB)	D35 G36
Binding residue (residue number reindexed from 1)	D37 G38
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.1.3.16: protein-serine/threonine phosphatase.

Gene Ontology

	Molecular Function
GO:0004722	protein serine/threonine phosphatase activity
GO:0016787	hydrolase activity
GO:0017018	myosin phosphatase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006470	protein dephosphorylation

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Molecular Function

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Biological Process

External links

PDB	RCSB:6iht, PDBe:6iht, PDBj:6iht
PDBsum	6iht
PubMed	30868877
UniProt	Q9RL81

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