Structure of PDB 6iej Chain A Binding Site BS03

Receptor Information
>6iej Chain A (length=126) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SYSHVFTVTVRKATNVTKGAIGDMLDTPDPYVELFIPSAPDCRKRTKHFN
NDVNPVWNETFEFILDPNQDNVLEVTLMDANYVMDETLGMATFPISSLKL
GEKKEVQLTFNNVTEMTLELSLEVCS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6iej Chain A Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6iej Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase A2alpha.
Resolution2.206 Å
Binding residue
(original residue number in PDB)		D66 N68
Binding residue
(residue number reindexed from 1)		D52 N54
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.4: phospholipase A2.
3.1.1.5: lysophospholipase.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0008289 lipid binding

View graph for
Molecular Function
External links
PDB RCSB:6iej, PDBe:6iej, PDBj:6iej
PDBsum6iej
PubMed31050338
UniProtP49147|PA24A_CHICK Cytosolic phospholipase A2 (Gene Name=PLA2G4A)

[Back to BioLiP]