Structure of PDB 6i0u Chain A Binding Site BS03

Receptor Information
>6i0u Chain A (length=350) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QAQVKARQHITVRLPKKARAMIVGEITNVFKDKYPIADKLKVIPEYDVIE
QDLCKLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGNTFHTFEH
RASNATVAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDI
CLNSMGFCNTNLLKYIFESQPLTQYMCIYVKNWLERCKLTEQISTYSITL
MVIYFLQLQALLPPIAMLQIEQAVLVGPWVVNFAQKSFSELGLQQLKATV
PVIKGFLRNFFAYFAKFDYEHFLVCPYIGQANVEIAKIERMLHARYSAYV
SDNPECSIQLKKPMVVQDPIQLNHNVTKAVTKYGLQTFVDYCQQTAELLE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6i0u Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6i0u Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
Resolution2.001 Å
Binding residue
(original residue number in PDB)		D278 D280 D343
Binding residue
(residue number reindexed from 1)		D84 D86 D149
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
External links
PDB RCSB:6i0u, PDBe:6i0u, PDBj:6i0u
PDBsum6i0u
PubMed30462292
UniProtQ9VI58|TUTT_DROME Terminal uridylyltransferase Tailor (Gene Name=Tailor)

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