Structure of PDB 6grc Chain A Binding Site BS03

Receptor Information

>6grc Chain A (length=406) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARG
GSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNGVSTAMAKRLIRLFGFTAH
DAPGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGSKGGP
PTHVTLHDAKKIAEGPSGLDREGMVLVALMSGGDYLPDGIPGCGIKVACQ
AAKAGFGKELCRIKRDKEAITEWKQRLLHELRTNESGFFRTKHKALEIPE
NFPNMEVLRYYTHPVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDW
TFRPGAIKLIKVLAPGLLVQRCLDRKKEESTLVKGISMRREHFSTDATPE
LRVSFIPAELVGLDPGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVEDW
EEGQRS

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

6grc Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	6grc A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1.
Resolution	2.452 Å
Binding residue (original residue number in PDB)	E122 D141 D143
Binding residue (residue number reindexed from 1)	E107 D126 D128
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004518	nuclease activity
GO:0008821	crossover junction DNA endonuclease activity

View graph for
Molecular Function

External links

PDB	RCSB:6grc, PDBe:6grc, PDBj:6grc
PDBsum	6grc
PubMed	30247722
UniProt	G0RYN2

[Back to BioLiP]