Structure of PDB 6eye Chain A Binding Site BS03

Receptor Information
>6eye Chain A (length=148) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSP
EDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVR
LSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG
Ligand information
Ligand IDKR
InChIInChI=1S/Kr
InChIKeyDNNSSWSSYDEUBZ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Kr]
FormulaKr
NameKRYPTON
ChEMBLCHEMBL1233877
DrugBank
ZINC
PDB chain6eye Chain A Residue 206 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6eye Mapping Hydrophobic Tunnels and Cavities in Neuroglobin with Noble Gas under Pressure.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		G110 L113 L114 W133 Y137
Binding residue
(residue number reindexed from 1)		G108 L111 L112 W131 Y135
Annotation score1
Enzymatic activity
Enzyme Commision number 1.7.-.-
Gene Ontology
Molecular Function
GO:0005092 GDP-dissociation inhibitor activity
GO:0005344 oxygen carrier activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0098809 nitrite reductase activity
Biological Process
GO:0015671 oxygen transport
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6eye, PDBe:6eye, PDBj:6eye
PDBsum6eye
PubMed29108649
UniProtQ9ER97|NGB_MOUSE Neuroglobin (Gene Name=Ngb)

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