Structure of PDB 6els Chain A Binding Site BS03

Receptor Information
>6els Chain A (length=459) Species: 3750 (Malus domestica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIIDFKLPAPAKLRIRPPAHAVDQAYRDKYYKAMELMKALPDDDPRSFKQ
QAAVHCAYCDGAYDQVGFPELELQIHNSWLFFPFHRYYLYFFEKILGKLI
NDPTFALPFWNWDSPAGMPLPAIYADPKSPLYDKLRSANHQPPTLVDLDY
NGTEDNVSKETTINANLKIMYRQMVSNSKNAKLFFGNPYRAGDEPDPGGG
SIEGTPHAPVHLWTGDNTQPNFEDMGNFYSAGRDPIFFAHHSNVDRMWSI
WKTLGGKRTDLTDSDWLDSGFLFYNENAELVRVKVRDCLETKNLGYVYQD
VDIPWLSSKPTPRRAKVAHAAVASSSKVVAGTEFPISLGSKISTVVKRPK
QKKRSKKAKEDEEEILVIEGIEFDRDVAVKFDVYVNDVDDLPSGPDKTEF
AGSFVSVPHSHKKMNTILRLGLTDLLEEIEAEDDDSVVVTLVPKFGAVKI
GGIKIEFAS
Ligand information
Ligand IDO
InChIInChI=1S/H2O/h1H2
InChIKeyXLYOFNOQVPJJNP-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		O
CACTVS 3.341[O]
FormulaO
NameOXYGEN ATOM
ChEMBLCHEMBL1098659
DrugBankDB09145
ZINC
PDB chain6els Chain A Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6els A Peptide-Induced Self-Cleavage Reaction Initiates the Activation of Tyrosinase.
Resolution1.346 Å
Binding residue
(original residue number in PDB)		H86 H238 H242 H272
Binding residue
(residue number reindexed from 1)		H55 H207 H211 H241
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H86 H107 H116 H238 H242 F259 H272
Catalytic site (residue number reindexed from 1) H55 H76 H85 H207 H211 F228 H241
Enzyme Commision number 1.10.3.1: catechol oxidase.
Gene Ontology
Molecular Function
GO:0004097 catechol oxidase activity
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:6els, PDBe:6els, PDBj:6els
PDBsum6els
PubMed30825403
UniProtP43309|PPO_MALDO Polyphenol oxidase, chloroplastic

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