Structure of PDB 6due Chain A Binding Site BS03

Receptor Information
>6due Chain A (length=737) Species: 507601 (Toxoplasma gondii GT1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YKGFQIWTDLAPSVKEEPDLMFAKCIVQAGTDKGNLTCVQIDPPGFDEPF
EVPQANAWNVNSLIDPMTYGDIGMLPHTNIPCVLDFLKVRFMKNQIYTTA
DPLVVAINPFRDLGNTTLDWIVRYRDTFDLSKLAPHVFYTARRALDNLHA
VNKSQTIIVSGESGAGKTEATKQIMRYFAAAKTGSMDLRIQNAIMAANPV
LEAFGNAKTIRNNNSSRFGRFMQLDVGREGGIKFGSVVAFLLEKSRVLTQ
DEQERSYHIFYQMCKGADAAMKERFHILPLSEYKYINPLCLDAPGIDDVA
EFHEVCESFRSMNLTEDEVASVWSIVSGVLLLGNVEVTATKDGGIDDAAA
IEGKNLEVFKKACGLLFLDAERIREELTVKVSYAGNQEIRGRWKQEDGDM
LKSSLAKAMYDKLFMWIIAVLNRSIKPPGGFKIFMGMLDIFGFEVFKNNS
LEQFFINITNEMLQKNFVDIVFDRESKLYRDEGVSSKELIFTSNAEVIKI
LTAKNNSVLAALEDQCLAPGGSDEKFLSTCKNALKGTTKFKPAKVSPNIN
FLISHTVGDIQYNAEGFLFKNKDVLRAEIMEIVQQSKNPVVAQLFAGIVG
QLIGSQFLSQLQSLMELINSTEPHFIRCIKPNDTKKPLDWVPSKMLIQLH
ALSVLEALQLRQLGYSYRRPFKEFLFQFKFIDLSASENPNLDPKEAALRL
LKSSKLPSEEYQLGKTMVFLKQTGAKELTQIQRECLS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6due Chain A Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6due Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA fromToxoplasma gondii.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		T200 S248
Binding residue
(residue number reindexed from 1)		T168 S216
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000146 microfilament motor activity
GO:0003774 cytoskeletal motor activity
GO:0003779 actin binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0051015 actin filament binding
Biological Process
GO:0007015 actin filament organization
GO:0030050 vesicle transport along actin filament
Cellular Component
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0016459 myosin complex
GO:0031982 vesicle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6due, PDBe:6due, PDBj:6due
PDBsum6due
PubMed30348763
UniProtS7W634

[Back to BioLiP]