Structure of PDB 6cme Chain A Binding Site BS03

Receptor Information
>6cme Chain A (length=154) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSV
YCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLA
TGDEFYLMEDGRLVCKEDYETAKGGTPLVAGSPIRHENAVQGSAVEVQTY
QPPW
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6cme Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6cme Mutation in a flexible linker modulates binding affinity for modular complexes.
Resolution1.92 Å
Binding residue
(original residue number in PDB)		C89 C92 H111 C114
Binding residue
(residue number reindexed from 1)		C64 C67 H86 C89
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6cme, PDBe:6cme, PDBj:6cme
PDBsum6cme
PubMed30788856
UniProtP53776;
Q9CXV0

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