Structure of PDB 6cim Chain A Binding Site BS03

Receptor Information
>6cim Chain A (length=611) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNE
HRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGR
QIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASS
VDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVV
VKESCDGMGDVSEKHGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKP
NSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPR
TFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSI
TRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHC
DIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPI
MRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSS
CPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEI
IERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTS
KYLQKFMNAHN
Ligand information
>6cim Chain G (length=52) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggtttttgtctggcttcacacttgatttgcatcactgtgtaagacaggcc
ag
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6cim Cracking the DNA Code for V(D)J Recombination.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		T400 A403 Y485 K489 Q495 H501 Q978
Binding residue
(residue number reindexed from 1)		T6 A9 Y91 K95 Q101 H107 Q582
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cim, PDBe:6cim, PDBj:6cim
PDBsum6cim
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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