Structure of PDB 6cil Chain A Binding Site BS03

Receptor Information
>6cil Chain A (length=585) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQG
RGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAE
KVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRF
RYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSE
KEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDH
ETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREV
EGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPY
HESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEV
YKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDA
VCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQR
FAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGQSGNKLFRRFR
KMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN
Ligand information
>6cil Chain G (length=53) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggtttttgtctggcttcacacttgatttgcatcactgtgtaagacaggcc
aga
Receptor-Ligand Complex Structure
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PDB6cil Cracking the DNA Code for V(D)J Recombination.
Resolution4.15 Å
Binding residue
(original residue number in PDB)		Y485 K489 Q495 H501 E607 Q978
Binding residue
(residue number reindexed from 1)		Y78 K82 Q88 H94 E200 Q556
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cil, PDBe:6cil, PDBj:6cil
PDBsum6cil
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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