Structure of PDB 6cij Chain A Binding Site BS03

Receptor Information
>6cij Chain A (length=614) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNE
HRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGR
QIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASS
VDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVV
VKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEP
KPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGI
PRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFH
SITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDAL
HCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLK
PIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWR
SSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVP
EIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLY
TSKYLQKFMNAHNA
Ligand information
>6cij Chain G (length=60) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgggtttttgtctggcttcacacttgatttgcatcactgtgtaagacagg
ccagatccag
Receptor-Ligand Complex Structure
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PDB6cij Cracking the DNA Code for V(D)J Recombination.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		L399 T400 A403 Y485 K489 P499 H501 K608 H609 G610 S611 Q978
Binding residue
(residue number reindexed from 1)		L5 T6 A9 Y91 K95 P105 H107 K214 H215 G216 S217 Q584
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cij, PDBe:6cij, PDBj:6cij
PDBsum6cij
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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