Structure of PDB 6cg6 Chain A Binding Site BS03

Receptor Information
>6cg6 Chain A (length=207) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFII
DEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDIN
DNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQ
GQPYFSVEPETGIIRTALPNMNRENKEQYQVVIQAKDMGGQMGGLSGTTT
VNITLTD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6cg6 Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6cg6 Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior.
Resolution2.707 Å
Binding residue
(original residue number in PDB)		N100 N102 D132 D134 S141 D187
Binding residue
(residue number reindexed from 1)		N100 N102 D132 D134 S141 D187
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6cg6, PDBe:6cg6, PDBj:6cg6
PDBsum6cg6
PubMed29742438
UniProtP70408|CAD10_MOUSE Cadherin-10 (Gene Name=Cdh10)

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