Structure of PDB 6bwh Chain A Binding Site BS03

Receptor Information
>6bwh Chain A (length=207) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DGDIGLIIAVKRLAAAKTRLAPVFSAQTRENVVLAMLVDTLTAAAGVGSL
RSITVITPDEAAAAAAAGLGADVLADPTPEDDPDPLNTAITAAERVVAEG
ASNIVVLQGDLPALQTQELAEAISAARHHRRSFVADRLGTGTAVLCAFGT
ALHPRFGPDSSARHRRSGAVELTGAWPGLRCDVDTPADLTAARQLGVGPA
TARAVAH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6bwh Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6bwh A revised biosynthetic pathway for the cofactor F420in prokaryotes.
Resolution2.18 Å
Binding residue
(original residue number in PDB)		D116 D188 D190
Binding residue
(residue number reindexed from 1)		D110 D182 D184
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.105: phosphoenolpyruvate guanylyltransferase.
Gene Ontology
Molecular Function
GO:0005525 GTP binding
GO:0016779 nucleotidyltransferase activity
GO:0043814 phospholactate guanylyltransferase activity
GO:0070568 guanylyltransferase activity
Biological Process
GO:0052645 F420-0 metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6bwh, PDBe:6bwh, PDBj:6bwh
PDBsum6bwh
PubMed30952857
UniProtP9WP83|FBID_MYCTU Phosphoenolpyruvate guanylyltransferase (Gene Name=fbiD)

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