Structure of PDB 6b9l Chain A Binding Site BS03
Receptor Information
>6b9l Chain A (length=174) Species:
9606
(Homo sapiens) [
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KEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMYSVCNVMSGD
QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAES
DLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRK
GFYLAFQDIGACVALLSVRVYYKK
Ligand information
>6b9l Chain J (length=6) Species:
9606
(Homo sapiens) [
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AHHHHA
Receptor-Ligand Complex Structure
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PDB
6b9l
Structure-Based Design of Novel EphA2 Agonistic Agents with Nanomolar Affinity in Vitro and in Cell.
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
Y123 K141 I142 S169 V170 G171
Binding residue
(residue number reindexed from 1)
Y97 K115 I116 S143 V144 G145
Enzymatic activity
Enzyme Commision number
2.7.10.1
: receptor protein-tyrosine kinase.
External links
PDB
RCSB:6b9l
,
PDBe:6b9l
,
PDBj:6b9l
PDBsum
6b9l
PubMed
30110533
UniProt
P29317
|EPHA2_HUMAN Ephrin type-A receptor 2 (Gene Name=EPHA2)
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