Structure of PDB 6anj Chain A Binding Site BS03

Receptor Information
>6anj Chain A (length=138) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GILDSMGRLENLGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPF
VKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVL
DYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6anj Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6anj Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Resolution1.698 Å
Binding residue
(original residue number in PDB)		D227 S230 R231 D233
Binding residue
(residue number reindexed from 1)		D103 S106 R107 D109
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005544 calcium-dependent phospholipid binding
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:6anj, PDBe:6anj, PDBj:6anj
PDBsum6anj
PubMed28923929
UniProtQ62747|SYT7_RAT Synaptotagmin-7 (Gene Name=Syt7)

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