Structure of PDB 5z4m Chain A Binding Site BS03

Receptor Information
>5z4m Chain A (length=350) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQHITVRLPKKARAMIVGEITNVFKDKYPIADKLKVIPEYDVIEQDLCKL
LSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGNTFHTFEHRASNAT
VAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECAICLNSMG
FCNTNLLKYIFESQPLTQYMCIYVKNWLERCKLTEQISTYSITLMVIYFL
QLQALLPPIAMLQIEDAANQAVLVGPWVVNFAQKSFSELGLQQLKATVPV
IKGFLRNFFAYFAKFDYEHFLVCPYIGQANVEIAKIERMLHARYSAYVSD
NPECSIQLKKPMVVQDPIQLNHNVTKAVTKYGLQTFVDYCQQTAELLEEP
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5z4m Chain A Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5z4m Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Resolution1.74 Å
Binding residue
(original residue number in PDB)		D278 D280
Binding residue
(residue number reindexed from 1)		D78 D80
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
External links
PDB RCSB:5z4m, PDBe:5z4m, PDBj:5z4m
PDBsum5z4m
PubMed30407553
UniProtQ9VI58|TUTT_DROME Terminal uridylyltransferase Tailor (Gene Name=Tailor)

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