Structure of PDB 5xut Chain A Binding Site BS03

Receptor Information

>5xut Chain A (length=1217) Species: 1410628 (Lachnospiraceae bacterium ND2006)

MSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGV
KKLLDRYYLSFINDVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEIN
LRKEIAKAFKGNEGYKSLFKKDIIETILPEFLDDKDEIALVNSFNGFTTA
FTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKH
EVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESGE
KIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSDEEV
LEVFRNTLNKNSEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKD
IFGEWNVIRDKWNAEYDDIHLVTEKYEDDRRKSFKKIGSFSLEQLQEYAD
ADLSVVEKLKEIIIQKVDEIYKVYGSSEKLFDADFVLEKSLKKNDAVVAI
MKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDILLKVDHIYD
AIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYL
AIMDKKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAY
YNPSEDIQKIYKNGTFKKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDF
NFSETEKYKDIAGFYREVEEQGYKVSFESASKKEVDKLVEEGKLYMFQIY
NKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFMRRASLKKEE
LVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKC
PKNIFKINTEVRVLLKHDDNPYVIGIDRGERNLLYIVVVDGKGNIVEQYS
LNEIINNFNGIRIKTDYHSLLDKKEKERFEARQNWTSIENIKELKAGYIS
QVVHKICELVEKYDAVIALEDLNSGFKNSRVKVEKQVYQKFEKMLIDKLN
YMVDKKSNPCATGGALKGYQITNKFESFKSMSTQNGFIFYIPAWLTSKID
PSTGFVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRT
DADYIKKWKLYSYGNRIRIFRNNVFDWEEVCLTSAYKELFNKYGINYQQG
DIRALLCEQSDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDG
IFYDSRNYEAQENAILPKNADANGAYNIARKVLWAIGQFKKAEDEKLDKV
KIAISNKEWLEYAQTSV

Ligand information

>5xut Chain D (length=9)

cgtcctcta

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5xut Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): K120 K121 G146 T148 T149 Q529 K591
• Binding residue (residue number reindexed from 1): K120 K121 G146 T148 T149 Q524 K586

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding

External links

• PDB: RCSB:5xut, PDBe:5xut, PDBj:5xut
• PDBsum: 5xut
• PubMed: 28781234
• UniProt: A0A182DWE3