Structure of PDB 5xfo Chain A Binding Site BS03

Receptor Information
>5xfo Chain A (length=315) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLW
KDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPA
PGEGEGTSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLD
WDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLY
GDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDR
EILPFTSENWDSLLLGELSDTPKGERSSRLLSALNSHKDRFISGREIKKR
KCLFGLHARMPPPVE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5xfo Chain A Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5xfo Polycomb-like proteins link the PRC2 complex to CpG islands
Resolution1.9 Å
Binding residue
(original residue number in PDB)		C189 C191 H212 C215
Binding residue
(residue number reindexed from 1)		C164 C166 H187 C190
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5xfo, PDBe:5xfo, PDBj:5xfo
PDBsum5xfo
PubMed28869966
UniProtO43189|PHF1_HUMAN PHD finger protein 1 (Gene Name=PHF1)

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