Structure of PDB 5x9a Chain A Binding Site BS03

Receptor Information

>5x9a Chain A (length=188) Species: 7719 (Ciona intestinalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NQKLAEELYKTSCQKHFTKTEVESLIICYKNLLEGLKMDRNLFRDILHQK
FNMTEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLDEKMEYTFT
VFDLNGDGYISREEMFQMLKTCLVPDEGIKDLVEIALKKMDHDHDSRLSK
KDFKDAVLIEPLLLEAFGKCLPDEKSSEIFEYHVLGVK

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

5x9a Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5x9a Crystal structure of a Ca2+-dependent regulator of flagellar motility reveals the open-closed structural transition
Resolution	1.85 Å
Binding residue (original residue number in PDB)	D152 D154 D156 R158 D163
Binding residue (residue number reindexed from 1)	D141 D143 D145 R147 D152
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding
GO:0045504	dynein heavy chain binding
GO:0046872	metal ion binding
GO:0048487	beta-tubulin binding
GO:0120152	calcium-dependent outer dynein arm binding
GO:0140659	cytoskeletal motor regulator activity

	Biological Process
GO:0060326	cell chemotaxis
GO:1901317	regulation of flagellated sperm motility

	Cellular Component
GO:0005930	axoneme
GO:0097729	9+2 motile cilium

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External links

PDB	RCSB:5x9a, PDBe:5x9a, PDBj:5x9a
PDBsum	5x9a
PubMed	29386625
UniProt	Q8T893

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