Structure of PDB 5x2h Chain A Binding Site BS03

Receptor Information
>5x2h Chain A (length=746) Species: 192222 (Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MARILAFDIGISSIGWAFSENDELKDCGVRIFTESLALPRRLARSARKRL
ARRKARLNHLKHLIANEFKLNYEDYQSFDESLAKAYKGSLISPYELRFRA
LNELLSKQDFARVILHIAKRRGYDDIKNKEKGAILKAIKQNEEKLANYQS
VGEYLYKEYFQKFKENSKEFTNVRNKKESYERCIAQSFLKDELKLIFKKQ
REFGFSFSKKFEEEVLSVAFYKRALKDFSHLVGNCSFFTDEKRAPKNSPL
AFMFVALTRIINLLNNLKNTEGILYTKDDLNALLNEVLKNGTLTYKQTKK
LLGLSDDYEFKGEKGTYFIEFKKYKEFISQDDLNEIAKDITLIKDEIKLK
KALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLVTPLMLEGKKYDEACN
ELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKVLNALLKK
YGKVHKINIELGGYIARLVLNYTKDYLDFLPLSDVHVEAKSGMLTSALRH
TWGFSAKDRNNHLHHAIDAVIIAYRQKVLDKIDEIFVSKPERKKPSGALH
EETFRKEEEFYQSYGGKEGVLKALELGKIRKVNGKIVKNGDMFRVDIFKH
KKTNKFYAVPIYTMDFALKVLPNKAVARSKKGEIKDWILMDENYEFCFSL
YKDSLILIQTKDMQEPEFVYYNAFTSSTVSLIVSKHDNKFETLSKNQKIL
FKNANEKEVIAKSIGIQNLKVFEKYIVSALGEVTKAEFRQREDFKK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5x2h Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems
Resolution2.3 Å
Binding residue
(original residue number in PDB)		R780 S801 Y802 N827 M830 Y850 K890 T913 S915
Binding residue
(residue number reindexed from 1)		R542 S563 Y564 N589 M592 Y612 K652 T675 S677
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:5x2h, PDBe:5x2h, PDBj:5x2h
PDBsum5x2h
PubMed28306506
UniProtQ0P897|CAS9_CAMJE CRISPR-associated endonuclease Cas9 (Gene Name=cas9)

[Back to BioLiP]