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Receptor Information

>5x2g Chain A (length=749) Species: 192222 (Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MARILAFDIGISSIGWAFSENDELKDCGVRIFTKGESLALPRRLARSARK
RLARRKARLNHLKHLIANEFKLNYEDYQSFDESLAKAYKGSLISPYELRF
RALNELLSKQDFARVILHIAKRRGYDDIKNKEKGAILKAIKQNEEKLANY
QSVGEYLYKEYFQKFKENSKEFTNVRNKKESYERCIAQSFLKDELKLIFK
KQREFGFSFSKKFEEEVLSVAFYKRALKDFSHLVGNCSFFTDEKRAPKNS
PLAFMFVALTRIINLLNNLKNTEGILYTKDDLNALLNEVLKNGTLTYKQT
KKLLGLSDDYEFKGEKGTYFIEFKKYKEFISQDDLNEIAKDITLIKDEIK
LKKALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLVTPLMLEGKKYDEA
CNELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKVLNALL
KKYGKVHKINIELGGGYIARLVLNYTKDYLDFLPLSDVHVEAKSGMLTSA
LRHTWGFSAKDRNNHLHHAIDAVIIAYRQKVLDKIDEIFVSKPERKKPSG
ALHEETFRKEEEFYQSYGGKEGVLKALELGKIRKVNGKIVKNGDMFRVDI
FKHKKTNKFYAVPIYTMDFALKVLPNKAVARSKKGEIKDWILMDENYEFC
FSLYKDSLILIQTKDMQEPEFVYYNAFTSSTVSLIVSKHDNKFETLSKNQ
KILFKNANEKEVIAKSIGIQNLKVFEKYIVSALGEVTKAEFRQREDFKK

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5x2g Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems
Resolution	2.4 Å
Binding residue (original residue number in PDB)	R780 S801 Y802 N827 G828 M830 Y850 K890 T913 S915
Binding residue (residue number reindexed from 1)	R545 S566 Y567 N592 G593 M595 Y615 K655 T678 S680

Enzyme Commision number

	Molecular Function
GO:0003676	nucleic acid binding
GO:0004519	endonuclease activity

PDB	RCSB:5x2g, PDBe:5x2g, PDBj:5x2g
PDBsum	5x2g
PubMed	28306506
UniProt	Q0P897\|CAS9_CAMJE CRISPR-associated endonuclease Cas9 (Gene Name=cas9)

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Structure of PDB 5x2g Chain A Binding Site BS03