Structure of PDB 5wjm Chain A Binding Site BS03

Receptor Information
>5wjm Chain A (length=216) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVVDGDP
LGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVG
IRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTF
NITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIA
RKDFDLLLVSLADEND
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5wjm Chain A Residue 2003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5wjm Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		E1733 E1789 D1820 I1821 D1823 D1856
Binding residue
(residue number reindexed from 1)		E18 E74 D105 I106 D108 D141
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5wjm, PDBe:5wjm, PDBj:5wjm
PDBsum5wjm
PubMed30033219
UniProtQ99PF4|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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