Structure of PDB 5u6n Chain A Binding Site BS03

Receptor Information
>5u6n Chain A (length=442) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGHVLAVPYPSQGHITPFRQFCKRLHFKGLKTTLALTTFVFNSINPDLSG
PISIATISDGYDHGGFETADSIDDYLKDFKTSGSKTIADIIQKHQTSDNP
ITCIVYDAFLPWALDVAREFGLVATPFFTQPCAVNYVYYLSYINNGSLQL
PIEELPFLELQDLPSFFSVSGSYPAYFEMVLQQFINFEKADFVLVNSFQE
LELHENELWSKACPVLTIGPTIPSIYLDQRIKSDTGYDLNLFESKDDSFC
INWLDTRPQGSVVYVAFGSMAQLTNVQMEELASAVSNFSFLWVVRSSEEE
KLPSGFLETVNKEKSLVLKWSPQLQVLSNKAIGCFLTHCGWNSTMEALTF
GVPMVAMPQWTDQPMNAKYIQDVWKAGVRVKTEKESGIAKREEIEFSIKE
VMEGERSKEMKKNVKKWRDLAVKSLNEGGSTDTNIDTFVSRV
Ligand information
Ligand IDGLN
InChIInChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChIKeyZDXPYRJPNDTMRX-VKHMYHEASA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC(=O)N)C(C(=O)O)N
OpenEye OEToolkits 1.5.0C(CC(=O)N)[C@@H](C(=O)O)N
ACDLabs 10.04O=C(N)CCC(N)C(=O)O
CACTVS 3.341N[CH](CCC(N)=O)C(O)=O
CACTVS 3.341N[C@@H](CCC(N)=O)C(O)=O
FormulaC5 H10 N2 O3
NameGLUTAMINE
ChEMBLCHEMBL930
DrugBankDB00130
ZINCZINC000001532526
PDB chain5u6n Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5u6n Differences in salicylic acid glucose conjugations by UGT74F1 and UGT74F2 from Arabidopsis thaliana.
Resolution2.001 Å
Binding residue
(original residue number in PDB)		V443 S444 V446
Binding residue
(residue number reindexed from 1)		V439 S440 V442
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.-
Gene Ontology
Molecular Function
GO:0008194 UDP-glycosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0035251 UDP-glucosyltransferase activity
GO:0052639 salicylic acid glucosyltransferase (ester-forming) activity
GO:0052640 salicylic acid glucosyltransferase (glucoside-forming) activity
GO:0052641 benzoic acid glucosyltransferase activity
GO:0080002 UDP-glucose:4-aminobenzoate acylglucosyltransferase activity
GO:0090704 nicotinate-O-glucosyltransferase activity
Biological Process
GO:0009696 salicylic acid metabolic process
GO:0010030 positive regulation of seed germination
GO:0018874 benzoate metabolic process
GO:0046482 para-aminobenzoic acid metabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5u6n, PDBe:5u6n, PDBj:5u6n
PDBsum5u6n
PubMed28425481
UniProtO22822|U74F2_ARATH UDP-glycosyltransferase 74F2 (Gene Name=UGT74F2)

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