Structure of PDB 5oug Chain A Binding Site BS03

Receptor Information
>5oug Chain A (length=205) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GEFQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVD
VVIWLQMSWTDHYLQWNVSEYPGVKQVSVPISSLWKPDILLYNAIERPEV
LTPQLALVNSSGHVQYLPSIRQRFSCDVSGVDTESGATCKLKFGSWTHHS
RELDLQMQEADISGYIPYSRFELVGVTQKRSERFYECCKEPYPDVTFTVT
FRKKG
Ligand information
Ligand ID9Z0
InChIInChI=1S/C8H10Br2N2O2/c9-5-4-6(12-7(5)10)8(14)11-2-1-3-13/h4,12-13H,1-3H2,(H,11,14)
InChIKeyUAVIBMSTKCBELE-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6c1c(c([nH]c1C(=O)NCCCO)Br)Br
ACDLabs 12.01O=C(c1cc(Br)c(Br)n1)NCCCO
CACTVS 3.385OCCCNC(=O)c1[nH]c(Br)c(Br)c1
FormulaC8 H10 Br2 N2 O2
Name4,5-dibromo-N-(3-hydroxypropyl)-1H-pyrrole-2-carboxamide
ChEMBL
DrugBank
ZINCZINC000003883299
PDB chain5oug Chain A Residue 1105 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5oug An allosteric binding site of the alpha 7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein.
Resolution2.57 Å
Binding residue
(original residue number in PDB)		Y7 E9 L10 L63 Q64 Y70 V107
Binding residue
(residue number reindexed from 1)		Y8 E10 L11 L64 Q65 Y71 V108
Annotation score1
Binding affinityPDBbind-CN: -logKd/Ki=2.77,Kd=1703.44uM
Gene Ontology
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UnboundLocalError		Python 3.6.8: /usr/bin/python3
Sun Nov 24 21:02:54 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()
   1435     title=pdb2title(pdbid)
   1436     if bs.startswith("BS"):
=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)
   1438     else:
   1439         if lig3:
pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '5oug', asym_id = 'A', bs = 'BS03', title = 'An allosteric binding site of the alpha 7 nicoti...led in a humanized acetylcholine-binding protein.'
 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='5oug', asym_id='A', bs='BS03', title='An allosteric binding site of the alpha 7 nicoti...led in a humanized acetylcholine-binding protein.')
   1295         display_ec(ec,csaOrig,csaRenu)
   1296     if go:
=> 1297         display_go(go,uniprot,pdbid,asym_id)
   1298     return pubmed,uniprot
   1299 
global display_go = <function display_go>, go = '0004888,0005216,0005230,0006811,0016020,0022848,0034220,0045211', uniprot = '', pdbid = '5oug', asym_id = 'A'
 /var/www/html/BioLiP/pdb.cgi in display_go(go='0004888,0005216,0005230,0006811,0016020,0022848,0034220,0045211', uniprot='', pdbid='5oug', asym_id='A')
    480         '''.replace("$namespace_link",namespace_link
    481           ).replace("$namespace",namespace
=>  482           ).replace("$uniprot",u
    483         ))
    484         for l,(term,name) in enumerate(go2aspect[Aspect]):
u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>