Structure of PDB 5nl1 Chain A Binding Site BS03

Receptor Information
>5nl1 Chain A (length=141) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMD
ESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEM
SRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQP
Ligand information
>5nl1 Chain K (length=27) Species: 623 (Shigella flexneri) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SHMTRETIFEASKKVTNSLSNLISLIG
Receptor-Ligand Complex Structure
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PDB5nl1 Shigella IpaA Binding to Talin Stimulates Filopodial Capture and Cell Adhesion.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
S501 Q504 A505
Binding residue
(residue number reindexed from 1)
S14 Q17 A18
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
Cellular Component
GO:0001726 ruffle
GO:0005925 focal adhesion

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Molecular Function

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Cellular Component
External links
PDB RCSB:5nl1, PDBe:5nl1, PDBj:5nl1
PDBsum5nl1
PubMed30673614
UniProtP26039|TLN1_MOUSE Talin-1 (Gene Name=Tln1)

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