Structure of PDB 5ngy Chain A Binding Site BS03

Receptor Information

>5ngy Chain A (length=1265) Species: 33964 (Leuconostoc citreum)

VPETITGGRYSLKDGYYVYLDKQGKQVVGPKNIDNHLQYFDETTGKQVKG
DFRSVNGKRIYFNANLGYADDYTTDVAGKLVGYDSNGNQVKAGYVTNSQG
KTYYFNNQGEAIIGLKTDNNKTQYFGPDGAQVKGAFQQVNGKNIYFDAQT
GYARQNVGFLDGTAKGFDEQGNQIKSGIATDLSGNVYYFDASGKMLTGVQ
NIDGKKYYFDEQGHRRRNYAGVFNNEFIYFGLDGVGQSAIEYQFEKGLTS
QNSVATSHNAAKSYDTKSFTNVDGFLTANSWYRPTDILRNGTKWEPSTET
DFRPLLMTWWPDKEVQANYLNYMSALGLGDQKIYTGASSQLDLNNAALIV
QEAIEKKISLEKSTKWLDDSIKSFIKSKRKDIQGNLVDTNPGWTIDSETG
STNHLQNGAFIFTNSPLVPEANAAEGNRLINRTPSQQTGNHISYASQPYS
GDDWGYELLLGNDVDNSNPIVQAEQLNWIHYLMNFGTITAPQDPDAHLAN
FDSIRIDAVDNVDADLLQIAGDYFKAAYQVGENDKNANQHIHILQDWSPN
DVWYNQQVNGNSQLTMDATMQNQLLASLTRPITSRDSMKSFTKDALLVHR
TADNSYNQAVPNYSFIRAHDSEVQTIIAKIISDKHPDLYPTVDKALLAKD
SALYDEAFTEYNADMQKISSQKQYTHNNMPSAYAILLTNKDTVPRVYYGD
LFTDNGEYMANKTPYYDAITSLLTARTKFVSGGQSLSVDKNDVLTSVRYG
KGALSATDNGSSDTRNQGIGVIVSNNPNLDLNNDKVTLSMGISHAHQAYR
PLLLTNSQGIVAYATDSEVPQNLYKTTNDKGELTFDASEIKGYDTVQTSG
YLAVWVPVGASDEQDARTIASTEKNNGNSVYHSNAALDSQLIYEGFSNFQ
TVPSKNASADEYANVIIAKHAADFNKWGVTSFQMAPQYRSSTDGSFLDAV
DTVQNGYAFTDRYDLGFNAADGSKNPTKYGTDEDLRNAIKSLHAQKTYDG
SSIQVMADFVPDQLYNMPLEQAVSVIRTDKYGVNSENPDIQNIIYAANIK
SSGTDYQSIYGGKYLAELQKNPLFKSLFDRIQISTKKTIDPNTRITQWSA
KYFNGSNIQGKGINYVLKDWASNKYFNVSSNDDMYSRLPKQLMNQESNTG
FIVDDIGVKYYSISGYQAKNTFVEDGNGEWYYFDNDGYMVKSTEESGPLR
TVNASSKKYYILPNGVEIRNSFGQDIQGNTYYFDARGEMVTSQYISDDTQ
NIYYFNNDGTMAKKG

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 5ngy Chain A Residue 1501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5ngy Investigations on the Determinants Responsible for Low Molar Mass Dextran Formation by DSR-M Dextransucrase
• Resolution: 3.7 Å
• Binding residue (original residue number in PDB): E627 D633 N681 V682 D1182
• Binding residue (residue number reindexed from 1): E457 D463 N511 V512 D1012
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.4.1.5: dextransucrase.

Gene Ontology

Molecular Function

• GO:0016757 glycosyltransferase activity
• GO:0046527 glucosyltransferase activity
• GO:0046872 metal ion binding
• GO:0047849 dextransucrase activity

Biological Process

• GO:0009250 glucan biosynthetic process

External links

• PDB: RCSB:5ngy, PDBe:5ngy, PDBj:5ngy
• PDBsum: 5ngy
• UniProt: A0A2H4A2Q1