Structure of PDB 5m0r Chain A Binding Site BS03

Receptor Information
>5m0r Chain A (length=276) Species: 36374 (Visna/maedi virus EV1 KV1772) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WIENIPLAEEEHNKWHQDAVSLHLEFGIPRTAAEDIVQQCDVCQENKMPS
TLRGSNKRGIDHWQVDYTHYEDKIILVWVETNSGLIYAERVKGETGQEFR
VQTMKWYAMFAPKSLQSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQ
ALVERTHQTLKNTLEKLIPMFNAFESALAGTLITLNIKRKGGLGTSPMDI
FIFNKEQQRIQQQSKSKQEKIRFCYYRTRKRGHPGEWQGPTQVLWGGDGA
IVVKDRGTDRYLVIANKDVKFIPPPK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5m0r A supramolecular assembly mediates lentiviral DNA integration.
Resolution8.2 Å
Binding residue
(original residue number in PDB)		E94 D118 N119 G120 P121 W145
Binding residue
(residue number reindexed from 1)		E94 D118 N119 G120 P121 W145
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5m0r, PDBe:5m0r, PDBj:5m0r
PDBsum5m0r
PubMed28059770
UniProtP35956|POL_VILVK Gag-Pol polyprotein (Gene Name=pol)

[Back to BioLiP]