Structure of PDB 5i0h Chain A Binding Site BS03

Receptor Information
>5i0h Chain A (length=731) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFFTEGTRVWLRENGQHFPSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQ
KVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILAS
VNPYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQC
ILISGESGAGKTESTKLILKFLSVISQQSLELSLKEKTSCVERAILESSP
IMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKNRVVR
QNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTISD
QESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFK
TALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLA
MALYACCFEWVIKKINSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNIN
YANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKKLGL
LALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRVAVNNFGVKHYAGE
VQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDRRPT
VSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYS
GMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPEDVRGKCTSLLQLY
DASNSEWQLGKTKVFLRESLEQKLEKRREEE
Ligand information
Ligand IDBEF
InChIInChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
InChIKeyOGIAHMCCNXDTIE-UHFFFAOYSA-K
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[Be-](F)(F)F
ACDLabs 10.04
CACTVS 3.341		F[Be-](F)F
FormulaBe F3
NameBERYLLIUM TRIFLUORIDE ION
ChEMBL
DrugBank
ZINC
PDB chain5i0h Chain A Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5i0h The myosin X motor is optimized for movement on actin bundles.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		S159 K163 N215 S218 S219 G437
Binding residue
(residue number reindexed from 1)		S157 K161 N213 S216 S217 G435
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) S159 G160 T164 N215 S218 S219 G437 E439
Catalytic site (residue number reindexed from 1) S157 G158 T162 N213 S216 S217 G435 E437
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5i0h, PDBe:5i0h, PDBj:5i0h
PDBsum5i0h
PubMed27580874
UniProtQ9HD67|MYO10_HUMAN Unconventional myosin-X (Gene Name=MYO10)

[Back to BioLiP]