Structure of PDB 5hda Chain A Binding Site BS03

Receptor Information
>5hda Chain A (length=121) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKAVANMQGEMDRKCKQ
VKEKCKEEFVEEIKKLATQHKQLISQTKKKQWCYNCEEEAMYHCCWNTSY
CSIKCQQEHWHAEHKRTCRRK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5hda Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5hda BS69/ZMYND11 C-Terminal Domains Bind and Inhibit EBNA2.
Resolution2.3899 Å
Binding residue
(original residue number in PDB)
C523 C526 C541 C545
Binding residue
(residue number reindexed from 1)
C83 C86 C101 C105
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity
Biological Process
GO:0034243 regulation of transcription elongation by RNA polymerase II

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:5hda, PDBe:5hda, PDBj:5hda
PDBsum5hda
PubMed26845565
UniProtQ15326|ZMY11_HUMAN Zinc finger MYND domain-containing protein 11 (Gene Name=ZMYND11)

[Back to BioLiP]