Structure of PDB 5h8y Chain A Binding Site BS03

Receptor Information
>5h8y Chain A (length=567) Species: 4577 (Zea mays) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKRSKVEIIKEKSNFLRYPLNEELVSEAPNINESAVQLIKFHGSYQQTDR
DVRGQKNYSFMLRTKNPCGKVPNQLYLAMDTLADEFGIGTLRLTTRQTFQ
LHGVLKKNLKTVLSTVIKNMGSTLGACGDLNRNVLAPAAPYVKKDILFAQ
QTAENIAALLTPQSGAYYDLWVDGEKIMSAEEPPEVTKARNDNSHGTNFP
DSPEPIYGTQYLPRKFKVAVTAAGDNSVDILTNDIGVVVVSDDAGEPIGF
NIYVGGGMGRTHRVETTFPRLADPLGYVPKEDILYAIKAIVVTQRENGRR
DDRKYSRMKYMIDRWGIDRFRAEVEKYYGKKFESFRPLPEWQFNSYLGWQ
EQGDGKLFYGVHVDNGRVGGQAKKTLREIIEKYNLDVSITPNQNLILCGI
DQAWREPITTALAQAGLLEPKDVDPLNLTAMACPALPLCPLAQTEAERGI
LPILKRIRAVFNKVGIKDSESVVVRITGCPNGCARPYMAELGFVGDGPKS
YQIWLGGTPNQSTLAESFMDKVKLDDIEKVLEPLFTYWNGTRQEGESFGS
FTNRTGFDKLKEVVNKW
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5h8y Chain A Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5h8y Structural and mutational studies of an electron transfer complex of maize sulfite reductase and ferredoxin.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		V424 N453 N455
Binding residue
(residue number reindexed from 1)		V363 N392 N394
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) R124 R193 K276 K278 P452 C494 C500 C540 C544
Catalytic site (residue number reindexed from 1) R63 R132 K215 K217 P391 C433 C439 C479 C483
Enzyme Commision number 1.8.7.1: assimilatory sulfite reductase (ferredoxin).
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0016002 sulfite reductase activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0050311 sulfite reductase (ferredoxin) activity
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0000103 sulfate assimilation
GO:0006790 sulfur compound metabolic process
GO:0009409 response to cold
GO:0019418 sulfide oxidation
GO:0045892 negative regulation of DNA-templated transcription
GO:1900160 plastid chromosome packaging
Cellular Component
GO:0009337 sulfite reductase complex (NADPH)
GO:0009507 chloroplast
GO:0009570 chloroplast stroma
GO:0010319 stromule
GO:0042644 chloroplast nucleoid

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5h8y, PDBe:5h8y, PDBj:5h8y
PDBsum5h8y
PubMed26920048
UniProtO23813|SIR_MAIZE Sulfite reductase [ferredoxin], chloroplastic (Gene Name=SIR)

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