Structure of PDB 5e63 Chain A Binding Site BS03

Receptor Information
>5e63 Chain A (length=293) Species: 771870 (Sordaria macrospora k-hell) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNPWAVVGFIDAEGSFMVRVRKNSKYKTGWLVVAIFSVTVDKKDLFLLES
LKTFFGGLGSIKKSGNSTFSYRIESSEQLTKIILPFFDKYSLITEKLGDY
LLFKKVLELMGTKEHLTQRGLEKIVSLKASINKGLSEELQAAFPQCVPTP
RPEINNKNIPDPFWLAGFVSGDGSFKSILKKSESIKVGFQSILVFQITQH
ARDVKLMESLISYLGCGFIEKDSRGPWLYYTVTNFSDIQGKIIPFFHQYK
IIGSAYGDYQDWCKIALIMQNKNHLTPEGLNEIRALKGGMNKG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5e63 The Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		K32 Y33 K34 K69 S71 E81 S82 H122 L123 D179 T205 Q206 H207 W234
Binding residue
(residue number reindexed from 1)		K25 Y26 K27 K62 S64 E74 S75 H115 L116 D172 T198 Q199 H200 W227
Enzymatic activity
Catalytic site (original residue number in PDB) G178 D179
Catalytic site (residue number reindexed from 1) G171 D172
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:5e63, PDBe:5e63, PDBj:5e63
PDBsum5e63
PubMed26705195
UniProtF7WD42

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