Structure of PDB 5dag Chain A Binding Site BS03

Receptor Information
>5dag Chain A (length=171) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCES
QERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPI
VLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQF
AGLLCQYCGYCKYHFSKLKKS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5dag Chain A Residue 303 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dag The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		C137 C140 H167 C170
Binding residue
(residue number reindexed from 1)		C114 C117 H144 C147
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dag, PDBe:5dag, PDBj:5dag
PDBsum5dag
PubMed26439302
UniProtP55197|AF10_HUMAN Protein AF-10 (Gene Name=MLLT10)

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