Structure of PDB 5d91 Chain A Binding Site BS03

Receptor Information

>5d91 Chain A (length=335) Species: 224325,288705

MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDY
LIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIE
KYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIGSRGLFAAIFLPIAR
LLADWGVSPDAVTVVGTLGVMAGALIFYPMGQLFWGTVVITVFVFSDIID
GLMARLLFREGPWGAFLDSYLDRVGDSSVFTGIVIWFFLGGANPTIAILA
LICLVLSSLVSYSKARAEGLGLTANVGIAERSERLVVVLVATGLVGLGIP
SWVLLVVLIVLAIASVVTIFQRVLTVREQAKAWTA

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 5d91 Chain A Residue 307

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5d91 Structural basis for phosphatidylinositol-phosphate biosynthesis.
• Resolution: 2.501 Å
• Binding residue (original residue number in PDB): D66 D87 D91
• Binding residue (residue number reindexed from 1): D197 D218 D222
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number:
  2.7.8.-

Gene Ontology

Molecular Function

• GO:0016780 phosphotransferase activity, for other substituted phosphate groups

Biological Process

• GO:0008654 phospholipid biosynthetic process

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:5d91, PDBe:5d91, PDBj:5d91
• PDBsum: 5d91
• PubMed: 26510127
• UniProt: A9WSF5;
  O27985