Structure of PDB 5d43 Chain A Binding Site BS03

Receptor Information

>5d43 Chain A (length=150) Species: 10090 (Mus musculus)

LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMIS
EVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK
NLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLYHH

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 5d43 Chain A Residue 1203

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5d43 Crystal Structure of Wild-Type Centrin 1 from Mus musculus Occupied by Ca2.
• Resolution: 2.82 Å
• Binding residue (original residue number in PDB): D114 D116 T118 K120 N125
• Binding residue (residue number reindexed from 1): D90 D92 T94 K96 N101
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0005509 calcium ion binding
• GO:0008017 microtubule binding
• GO:0031683 G-protein beta/gamma-subunit complex binding
• GO:0032795 heterotrimeric G-protein binding
• GO:0046872 metal ion binding

Biological Process

• GO:0034605 cellular response to heat
• GO:0051301 cell division

Cellular Component

• GO:0000922 spindle pole
• GO:0005737 cytoplasm
• GO:0005813 centrosome
• GO:0005814 centriole
• GO:0005815 microtubule organizing center
• GO:0005829 cytosol
• GO:0005856 cytoskeleton
• GO:0005929 cilium
• GO:0032391 photoreceptor connecting cilium
• GO:0042995 cell projection

External links

• PDB: RCSB:5d43, PDBe:5d43, PDBj:5d43
• PDBsum: 5d43
• PubMed: 29037133
• UniProt: P41209|CETN1_MOUSE Centrin-1 (Gene Name=Cetn1)