Structure of PDB 5cnq Chain A Binding Site BS03

Receptor Information

>5cnq Chain A (length=392) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARG
GSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNKPGVSTAMAKRLIRLFGFT
AHDAPGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGGPP
THVTLHDAKKIAEGPSGLDREGMVLVALMSGGGIPGCGIKVACQAAKAGF
GKELCAITEWKQRLLHELRTNESGFFRTKHKALEIPENFPNMEVLRYYTH
PVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDWTFRPGAIKLIKVL
APGLLVQRCLDRYEESTLVKGISMRREHFSTDATPELRVSFIPAELVGLD
PGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVEDWEEGQRS

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

5cnq Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5cnq Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.
Resolution	2.602 Å
Binding residue (original residue number in PDB)	D141 D143
Binding residue (residue number reindexed from 1)	D128 D130
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004518	nuclease activity
GO:0008821	crossover junction DNA endonuclease activity

View graph for
Molecular Function

External links

PDB	RCSB:5cnq, PDBe:5cnq, PDBj:5cnq
PDBsum	5cnq
PubMed	26686639
UniProt	G0RYN2

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