Structure of PDB 5aws Chain A Binding Site BS03

Receptor Information
>5aws Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGAQDTLPVAAAFTETVNAYFKGADPSKCIVKITGEMVLSFPAGITRHFA
NNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQNDANTKEFWVNMPNLM
THLKKVSEQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCEPSSTDL
RIDYKYNTDAMTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRIL
WKIPDISQKSENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDI
ELVGAGYRFSLIKKRFAAGKYLADN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5aws Chain A Residue 905 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5aws Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
Resolution2.001 Å
Binding residue
(original residue number in PDB)		D558 H601
Binding residue
(residue number reindexed from 1)		D5 H48
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0072583 clathrin-dependent endocytosis

View graph for
Biological Process
External links
PDB RCSB:5aws, PDBe:5aws, PDBj:5aws
PDBsum5aws
PubMed26822536
UniProtQ9BQI5|SGIP1_HUMAN SH3-containing GRB2-like protein 3-interacting protein 1 (Gene Name=SGIP1)

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