Structure of PDB 5abq Chain A Binding Site BS03

Receptor Information
>5abq Chain A (length=312) Species: 5323 (Pleurotus eryngii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CDDGRTTANAACCILFPILDDIQENLFDGAQCGEEVHESLRLTFHDCIGF
SPTLGGGGCDGSIIAFSDIETNFPANAGIDEIVEAQKPFVAKHNISAGDF
IQFAGAVGVSNCPGGVRIPFFLGRPDAVKASPDHLVPEPFDSVTSILARM
GDAGFSPVEVVWLLASHSIAAADKVDPSIPGTPFDSTPGVFDSQFFIETL
LKGRLFPGTADNKGEAQSPLQGEIRLQSDELLARDPRTACEWQSMVNNQP
KIQNRFAATMSKMALLGQDKTKLIDCSDVIPTPPALVGAAHLPAGFSLKD
VEQACRKTPFPR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5abq Chain A Residue 1316 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5abq Improving the Ph-Stability of Versatile Peroxidase by Comparative Structural Analysis with a Naturally-Stable Manganese Peroxidase.
Resolution2.293 Å
Binding residue
(original residue number in PDB)		S170 D187 T189 V192 D194
Binding residue
(residue number reindexed from 1)		S168 D185 T187 V190 D192
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) R43 H47 H169 F186 D231
Catalytic site (residue number reindexed from 1) R41 H45 H167 F184 D229
Enzyme Commision number 1.11.1.16: versatile peroxidase.
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0016689 manganese peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0052750 reactive-black-5:hydrogen-peroxide oxidoreductase activity
Biological Process
GO:0000302 response to reactive oxygen species
GO:0006979 response to oxidative stress
GO:0034599 cellular response to oxidative stress
GO:0042744 hydrogen peroxide catabolic process
GO:0046274 lignin catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5abq, PDBe:5abq, PDBj:5abq
PDBsum5abq
PubMed26496708
UniProtO94753|VPL2_PLEER Versatile peroxidase VPL2 (Gene Name=vpl2)

[Back to BioLiP]