Structure of PDB 5a68 Chain A Binding Site BS03

Receptor Information

>5a68 Chain A (length=203) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GAMEVEVKLRLLTAAAHLRLTTLLTPYHLKTLHQRNTFFDTPKNDLSLRR
AVLRLRFLQNAPSPPRCIVSLKAKPTLANGISRVEEDEEEIEYWIGKECV
ESPAKLSDIGSRVLKRVKEEYGFNDFLGFVCLGGFENVRNVYEWRGVKLE
VDETKYDFGNCYEIECETEEPERVKTMIEEFLTEEKIEFSNSDMTKFAVF
RSG

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

5a68 Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	5a68 Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes.
Resolution	1.67 Å
Binding residue (original residue number in PDB)	E2 K76 E90
Binding residue (residue number reindexed from 1)	E4 K72 E86
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.6.1.-
3.6.1.25: triphosphatase.

Gene Ontology

	Molecular Function
GO:0005524	ATP binding
GO:0016462	pyrophosphatase activity
GO:0016787	hydrolase activity
GO:0016887	ATP hydrolysis activity
GO:0050355	inorganic triphosphate phosphatase activity

	Biological Process
GO:0048364	root development

	Cellular Component
GO:0005634	nucleus
GO:0005680	anaphase-promoting complex
GO:0005737	cytoplasm

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External links

PDB	RCSB:5a68, PDBe:5a68, PDBj:5a68
PDBsum	5a68
PubMed	26221030
UniProt	Q9SIY3\|TTM3_ARATH Triphosphate tunnel metalloenzyme 3 (Gene Name=TTM3)

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