Structure of PDB 4zu9 Chain A Binding Site BS03

Receptor Information
>4zu9 Chain A (length=582) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKYILFATAGHVDHGKTTLIKTLTGIDTDRLPEEKKRGLSIDIGFAYIDF
PDINTRLEIIDVPGHERFIKNAIAGICSASGLILVVDPNEGIMPQTIEHL
RVAKSFGIKHGIAVLTKMDKVDEELAHIAEEELIAFLEKEEMNMEIVKVS
AVTGQGIEDLKNSIKKLLESINNLNKHKPLRIFVDSAFVVKGYGTVLRGS
CFEGEVKEGDKVVVEPIGVISRVRKMQNHGVFVKKAVAGERIALNLPEVD
AKKVKRGFLILKPESYEKSNVLIVKTEIDLKPGKIYQVFFGMRETVGKIS
VIDKGIYLVRLKENAIVRRGDKLVVLDSSGNFLGGAEVLHPKVRVTKKAF
IKKNIKDLLENFECYLLKERGPIGLKLEFFKRITGVSPKVANLKPESIEI
RGVYYLKGFIENLKLKIKKFLDTELQNAFGVDKEKVKSMFSLNEELLKYI
LDELKTYKIVNELIIDERKSDLEKNEDFQKLMSILKGGIKEEREIILEGI
PKEILTLSIKRKYAHRIGEYLIISDELLKKYINELKELGKTFNVQQAKNK
LGLTRKYLIPLLEYLDYLGLTVREGNERRWKR
Ligand information
Ligand IDCYS
InChIInChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
InChIKeyXUJNEKJLAYXESH-REOHCLBHSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](CS)C(O)=O
OpenEye OEToolkits 1.5.0C([C@@H](C(=O)O)N)S
CACTVS 3.341N[C@@H](CS)C(O)=O
ACDLabs 10.04O=C(O)C(N)CS
OpenEye OEToolkits 1.5.0C(C(C(=O)O)N)S
FormulaC3 H7 N O2 S
NameCYSTEINE
ChEMBLCHEMBL863
DrugBankDB00151
ZINCZINC000000895042
PDB chain4zu9 Chain A Residue 2006 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4zu9 Crystal structure of the full-length bacterial selenocysteine-specific elongation factor SelB
Resolution3.191 Å
Binding residue
(original residue number in PDB)		R30 R198 H229 R241
Binding residue
(residue number reindexed from 1)		R30 R198 H229 R241
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D13 K16 T17 S40 H65
Catalytic site (residue number reindexed from 1) D13 K16 T17 S40 H65
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0046872 metal ion binding
Biological Process
GO:0001514 selenocysteine incorporation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4zu9, PDBe:4zu9, PDBj:4zu9
PDBsum4zu9
PubMed26304550
UniProtO67141

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