Structure of PDB 4yzt Chain A Binding Site BS03

Receptor Information
>4yzt Chain A (length=512) Species: 1402 (Bacillus licheniformis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ITPADLLENMSPGWNLGNTLDAVPTEGSWNNPPVREHTFDDIRDAGFKSV
RIPVTWDSHIGSAPEYPIDTDWMNRVEEVTDWALEREFYVVLNIHHDSWL
WISRMGNSQQETLDKLGKVWKQIAERFKNKSERLLFEIVNEPTGMSAYQM
NLLNREMLNIIRSTGGKNGQRLVIVGGLEDNKDELLHSFEPPDDDRIVLT
YHYYSPWDYVSNWWGRTTWGSAAEISEMEEDIKPVYEKFVREGYPVIIGE
YGTLGANEKHSKWLYHDTFVRLAHKYQMVPMWWDNGNDQFDRAERQWRDP
VVKEIVIQAGRGVPNAIIKPADLFIKKGQSISDQTVDIQLNGNVLTGIYQ
KSEPLKEGSDYTVDNAGKTVSIKASCLAKLLGQPGVKAQLTFTFHKGASQ
VMDIILYDDPKLEKSEFTISQSAISGDLKIPASLNGTKLATVKGVVDSTG
RPVLEEVWSWTPYLNYDEDFYEKDGDLYLKERVLKYLKSDSTFTFELWPK
GVEAVVKVKITP
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain4yzt Chain B Residue 3 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4yzt Molecular characterization of a family 5 glycoside hydrolase suggests an induced-fit enzymatic mechanism.
Resolution1.665 Å
Binding residue
(original residue number in PDB)		N36 W47 N48
Binding residue
(residue number reindexed from 1)		N18 W29 N30
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.4: cellulase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0008422 beta-glucosidase activity
GO:0008810 cellulase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0009251 glucan catabolic process
GO:0030245 cellulose catabolic process
Cellular Component
GO:0005576 extracellular region
GO:0009986 cell surface

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4yzt, PDBe:4yzt, PDBj:4yzt
PDBsum4yzt
PubMed27032335
UniProtQ65JI7

[Back to BioLiP]