Structure of PDB 4v15 Chain A Binding Site BS03

Receptor Information

>4v15 Chain A (length=373) Species: 85698 (Achromobacter xylosoxidans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RGIALPPAAQPGDPLARVDTPSLVLDLPAFEANLRAMQAWADRHEVALRP
HAKAHKCPEIALRQLALGARGICCQKVSEALPFVAAGIRDIHISNEVVGP
AKLALLGQLARAAKISVCVDNAENLAQLSAAMTRAGAEIDVLVEVDVGQG
RCGVSDDATVLALAQQARALPGLNFAGLQAYHGSVQHYRTREERAAVCRQ
AARIAASYAQLLRESGIACDTITGGGTGSVEFDAASGVYTELQAGSYAFM
DSDYGANEWNGPLKFQNSLFVLSTVMSTPAPGRVILDAGLKSTTAECGPP
AVYGEPGLTYAAINDEHGVVRVEPGAQAPALGAVLRLVPSHVDPTFNLHD
GLVVVKDGVVQDVWEIAARGFSR

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

4v15 Chain A Residue 1382 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4v15 The Crystal Structure of D-Threonine Aldolase from Alcaligenes Xylosoxidans Provides Insight Into a Metal Ion Assisted Plp-Dependent Mechanism.
Resolution	1.5 Å
Binding residue (original residue number in PDB)	H347 D349
Binding residue (residue number reindexed from 1)	H341 D343
Annotation score	1

Enzymatic activity

Enzyme Commision number

4.1.2.42: D-threonine aldolase.

Gene Ontology

	Molecular Function
GO:0008721	D-serine ammonia-lyase activity
GO:0016829	lyase activity
GO:0043876	D-threonine aldolase activity
GO:0046872	metal ion binding

	Biological Process
GO:0036088	D-serine catabolic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:4v15, PDBe:4v15, PDBj:4v15
PDBsum	4v15
PubMed	25884707
UniProt	A0A0J9X243

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