Structure of PDB 4us4 Chain A Binding Site BS03

Receptor Information
>4us4 Chain A (length=433) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GFILAAMGSAVGLGNIWRFSYVTGENGGAAFLLVYLGFIALIGIPIVLAE
FTIGRRAQSDAVGSFEKLAPGKPWKVAGLMGVAAGFLILSFYGVIAGWIL
FYLFNYITGQLWSAPAEGFGGFFEGFIANPTLPLFWQALFMIATIWIVAI
GVKKGIERSNKILMPLLGVLLIALAIYSLTLGGAKEGLAFLFSPDWSALK
DPGVYLAAISQAFFTLSLGMGALITYGSYVSKDSRLPGAAVSVAGLDTAF
AIIAGIMIFPAVFALGLSPSGGPGLVFVVLPDIFDSIRLGPIVGIAFFIL
LGAAALSSAVSLLEVPVAYFMRKFDWSRKQAAITLGVIITLLGIPSSLSF
GVLGEVTIIPGLNIFDSVDFIASSVFLPLGGMIIALFIGWGWKTSDALAE
SDLTDSVWGKLWILSLRFIAPIAILIVFLSAFQ
Ligand information
Ligand IDNA
InChIInChI=1S/Na/q+1
InChIKeyFKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Na+]
FormulaNa
NameSODIUM ION
ChEMBL
DrugBankDB14516
ZINC
PDB chain4us4 Chain A Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4us4 A Mechanism for Intracellular Release of Na+ by Neurotransmitter/Sodium Symporters
Resolution2.6 Å
Binding residue
(original residue number in PDB)		A26 V27 N31 T231 D263
Binding residue
(residue number reindexed from 1)		A10 V11 N15 T215 D247
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4us4, PDBe:4us4, PDBj:4us4
PDBsum4us4
PubMed25282149
UniProtQ9KDT3

[Back to BioLiP]