Structure of PDB 4tvc Chain A Binding Site BS03

Receptor Information
>4tvc Chain A (length=1036) Species: 1245 (Leuconostoc mesenteroides) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGLRQDSNGKLRYFDLTTGIQAKGQFVTIGQETYYFSKDHGDAQLLPMVT
EGHYGTITAWVYRDQNNTILKGLQNINGTLQFFDPYTGEQLKGGVAKYDD
KLFYFESGKGNLVSTVAGDYQDGHYISQDGQTRYADKQNQLVKGLVTVNG
ALQYFDNATGNQIKNQQVIVDGKTYYFDDKGNGEYLFTNTLDMSTNAFST
KNVAFNHDSSSFDHTVDGFLTADTWYRPKSILANGTTWRDSTDKDMRPLI
TVWWPNKNVQVNYLNFMKANGLLTTAAQYTLHSDQYDLNQAAQDVQVAIE
RRIASEHGTDWLQKLLFESQNNNPSFVKQQFIWNKDSEYHGGGDAWFQGG
YLKYGNNPLTPTTNSDYRQPGNAFDFLLANDVDNSNPVVQAENLNWLHYL
MNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAK
ANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGKNKPLTNM
LQDVDGGTLITDHTQNSTENQATPNYSIIHAHDKGVQEKVGAAITDATGA
DWTNFTDEQLKAGLELFYKDQRATNKKYNSYNIPSIYALMLTNKDTVPRM
YYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSVDNHGLLKS
VRFGKDAMTANDLGTSATRTEGLGVIIGNDPKLQLNDSDKVTLDMGAAHK
NQKYRAVILTTRDGLATFNSDQAPTAWTNDQGTLTFSNQEINGQDNTQIR
GVANPQVSGYLAVWVPVGASDNQDARTAATTTENHDGKVLHSNAALDSNL
IYEGFSNFQPKATTHDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDH
TFLDSTIDNGYAFTDRYDLGFNTPTKYGTDGDLRATIQALHHANMQVMAD
VVDNQVYNLPGKEVVSATRAGVYGNDDATGFGTQLYVTNSVGGGQYQEKY
AGQYLEALKAKYPDLFEGKAYDYWYKNYANDGSNPYYTLSHGDRESIPAD
VAIKQWSAKYMNGTNVLGNGMGYVLKDWHNGQYFKL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4tvc Chain A Residue 3000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4tvc Structural Insights into the Carbohydrate Binding Ability of an alpha-(12) Branching Sucrase from Glycoside Hydrolase Family 70.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		D2164 D2170 F2214 N2693
Binding residue
(residue number reindexed from 1)		D375 D381 F425 N904
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.5: dextransucrase.
Gene Ontology
Molecular Function
GO:0046527 glucosyltransferase activity
Biological Process
GO:0009250 glucan biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4tvc, PDBe:4tvc, PDBj:4tvc
PDBsum4tvc
PubMed26865636
UniProtQ8G9Q2

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