Structure of PDB 4r34 Chain A Binding Site BS03

Receptor Information
>4r34 Chain A (length=384) Species: 1885 (Streptomyces actuosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDFVLPELEDVRAEAATVDTRAVLALAEGEEPAESRAAVALALWEDRSIG
TAELQAAAEARCGARRPRLHTFVPLYTTNYCDSECKMCSMRKGNHRLDRK
FSGRKEITEQLEILYHHEGVRGVGFLTGEYEDKHTRLASAFRIGWAIRTA
LDLGFERVYFNIGSMEQDEIDVLGEWIGREDPVTMCVFQESYDRETYRRF
MGKTSVGVPKADFDRRVVSFDRWLDAGYRYVNPGVLVGLHDDLSAELVSL
VAHGDHLRSRGATADLSVPRMRPAMKSRDTTRVGDDDYLRLMSVVAFTCP
EQRLVLTTREPQEFQDVALGLAGVISPGSPDVAPYRAGCEARNDEKSSQF
LVADLRRPRHILGRIEASGTPVDHFVNPAGEASR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain4r34 Chain A Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4r34 Crystal Structure of Tryptophan Lyase (NosL): Evidence for Radical Formation at the Amino Group of Tryptophan.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		C95 S97 C99 C102 M104 R105 K224
Binding residue
(residue number reindexed from 1)		C81 S83 C85 C88 M90 R91 K210
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:4r34, PDBe:4r34, PDBj:4r34
PDBsum4r34
PubMed25196319
UniProtC6FX51

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