Structure of PDB 4qt6 Chain A Binding Site BS03

Receptor Information
>4qt6 Chain A (length=159) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GFDPEKAQCCLVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENR
GNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQ
GDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGEK
VKICDMQMR
Ligand information
Ligand IDARF
InChIInChI=1S/CH3NO/c2-1-3/h1H,(H2,2,3)
InChIKeyZHNUHDYFZUAESO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)N
CACTVS 3.341NC=O
ACDLabs 10.04O=CN
FormulaC H3 N O
NameFORMAMIDE
ChEMBLCHEMBL266160
DrugBank
ZINC
PDB chain4qt6 Chain A Residue 2204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4qt6 Crystal structure of the SPRY domain of human HERC1
Resolution1.64 Å
Binding residue
(original residue number in PDB)
F2136 R2192
Binding residue
(residue number reindexed from 1)
F103 R159
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.2.26: HECT-type E3 ubiquitin transferase.
External links
PDB RCSB:4qt6, PDBe:4qt6, PDBj:4qt6
PDBsum4qt6
PubMed
UniProtQ15751|HERC1_HUMAN Probable E3 ubiquitin-protein ligase HERC1 (Gene Name=HERC1)

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