Structure of PDB 4qqz Chain A Binding Site BS03

Receptor Information
>4qqz Chain A (length=903) Species: 269800 (Thermobifida fusca YX) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPLDLRFWAKERGLRGKTYPLVCHSLDAAAAALVLWNEYLSPGLRDTIAS
SMETDEEHAGHCIAFWAGLHDIGKLTREFQQQIAIDLSAYPGEELSGEQR
SHAAATGKWLPFALPSLGYPNGGLVTGLVAQMLGGHHGTFHPHPSFQSRN
PLAEFGFSSPHWEKQRHALLHAVFDATGRPTPPDMLDGPTASVVCGLVIL
ADWLVSQEDFLLERLTSLPADGSASALRAHFETSLRRIPSLLDAAGLRPI
TVPPATFTESFPHLSKPNGLQASLAKHLPCLCTGPGLVLITAPMGEGKTE
AAYHVADLLGKATGRPGRFLALPTMATADQMHTRLKEYARYRVEPRSSTL
ALLHSMAWLNPDYAPALGHRDPFAATDWLMGRKRGLLAPWAVGTIDQALM
AVLRAKHNALRLFGLAGKVVVVDEAHAVDPYMQVLLEQLLRWLGTLDVPV
VLLSATLHHSIANSLVKAYLEGARGRRWNRSEPQPVSEVSYPGWLHVDAR
IGKVTRSSDVDPLPIATTPRKPLEVRLVDVPVKEGALNRSTVLAKELTPL
VKQGGCAAIICTTVAEAQGVYDLLSQWFATLAPDLYLLHSRFPNRQRTEI
TATIVDLFGKEGAQSGRRPTAVLVATQVVEQSLDLDVDLMISDLAPVSLL
LQRAGRCWRHEHLGIINRPQWAKQPELVVLTPEQNRAPWFPRSWTSVYPL
ALLQRTYTLLRRRNGAPVQIPEDVQQLVDDVYDDDSLAEDLEADMERMGE
ELAQRGLARNAVIPDPDDAEDNLNGLTEFSFHVLATRFGAGSVRVLCYYV
DTAGNRWLDPECTVEFPEQGTGREGRFTMADCRDLVARTIPVRMGPWASQ
LTEDNHPPEAWRESFYLRDLVLIPQRVTDEGAVLPTETGGREWLLDPCKG
LIF
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain4qqz Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4qqz Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Resolution2.93 Å
Binding residue
(original residue number in PDB)		H37 H83 D84 D215
Binding residue
(residue number reindexed from 1)		H24 H70 D71 D202
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0051607 defense response to virus
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qqz, PDBe:4qqz, PDBj:4qqz
PDBsum4qqz
PubMed25132177
UniProtQ47PJ0

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