Structure of PDB 4pk0 Chain A Binding Site BS03

Receptor Information

>4pk0 Chain A (length=171) Species: 10665 (Tequatrovirus T4)

MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAI
GRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALI
NMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVI
TTFRTGTWDAYKNLCAHPGAA

Ligand information

• Ligand ID: T55
• InChI: InChI=1S/C10H20O2/c1-9(2)7-5-3-4-6-8-10(11)12/h9H,3-8H2,1-2H3,(H,11,12)
• InChIKey: OAOABCKPVCUNKO-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.352: CC(C)CCCCCCC(O)=O
  ACDLabs 10.04: O=C(N)CCCCCCC(C)C
  OpenEye OEToolkits 1.6.1: CC(C)CCCCCCC(=O)O
• Formula: C10 H20 O2
• Name: 8-METHYLNONANOIC ACID
• ZINC: ZINC000002043770
• PDB chain: 4pk0 Chain A Residue 201

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4pk0 X-ray Crystal Structure of Teicoplanin A2-2 Bound to a Catalytic Peptide Sequence via the Carrier Protein Strategy.
• Resolution: 2.3 Å
• Binding residue (original residue number in PDB): R8 I29 E64
• Binding residue (residue number reindexed from 1): R8 I29 E64
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.2.1.17: lysozyme.

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds

Biological Process

• GO:0009253 peptidoglycan catabolic process
• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0044659 viral release from host cell by cytolysis

Cellular Component

• GO:0030430 host cell cytoplasm

External links

• PDB: RCSB:4pk0, PDBe:4pk0, PDBj:4pk0
• PDBsum: 4pk0
• PubMed: 25147913
• UniProt: D9IEF7