Structure of PDB 4nod Chain A Binding Site BS03
Receptor Information
>4nod Chain A (length=190) Species:
9606
(Homo sapiens) [
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SVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPD
SKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAM
TKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLS
DSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRR
Ligand information
>4nod Chain D (length=22) [
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ccaaccaagccccataccccaa
Receptor-Ligand Complex Structure
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PDB
4nod
Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
Resolution
2.897 Å
Binding residue
(original residue number in PDB)
Y57 T78 I81 A85 W88 R89 Y103 W107 R140 R157 N163 A167 F170 P178
Binding residue
(residue number reindexed from 1)
Y14 T35 I38 A42 W45 R46 Y60 W64 R97 R114 N120 A124 F127 P135
Binding affinity
PDBbind-CN
: Kd=7.1nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4nod
,
PDBe:4nod
,
PDBj:4nod
PDBsum
4nod
PubMed
24435062
UniProt
Q00059
|TFAM_HUMAN Transcription factor A, mitochondrial (Gene Name=TFAM)
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