Structure of PDB 4nj5 Chain A Binding Site BS03

Receptor Information
>4nj5 Chain A (length=482) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PESERQFREHVRKTRMIYDSLRMFLMMEEAKRRARADGKAGKAGSMMRDC
MLWMNRDKRIVGSIPGVQVGDIFFFRFELCVMGLHGHPQSGIDFLTGSLS
SNGEPIATSVIVSGGDVIMYTGQGGQDRLGRQAEHQRLEGGNLAMERSMY
YGIEVRVIRGLKYENEVSSRVYVYDGLFRIVDSWFDVGKSGFGVFKYRLE
RIEGQAEMGSSVLKFARTLKTNPLSVRPRGYINFDISNGKENVPVYLFND
IDSDQEPLYYEYLAQTSFPPGLFGNASGCDCVNGCGSGCLCEAKNSGEIA
YDYNGTLIRQKPLIHECGSACQCPPSCRNRVTQKGLRNRLEVFRSLETGW
GVRSLDVLHAGAFICEYAGVALTREQANILTMNGDTLVYPARFSSARWED
WGDLSQVLADFERPSYPDIPPVDFAMDVSKMRNVACYISHSTDPNVIVQF
VLHDHNSLMFPRVMLFAAENIPPMTELSLDYG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4nj5 Chain A Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4nj5 SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		C434 C436 C440 C444
Binding residue
(residue number reindexed from 1)		C279 C281 C285 C289
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) Y522 Y636
Catalytic site (residue number reindexed from 1) Y367 Y481
Enzyme Commision number 2.1.1.43: Transferred entry: 2.1.1.354.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0042054 histone methyltransferase activity
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Cellular Component
External links
PDB RCSB:4nj5, PDBe:4nj5, PDBj:4nj5
PDBsum4nj5
PubMed24463519
UniProtQ9T0G7|SUVH9_ARATH Histone-lysine N-methyltransferase family member SUVH9 (Gene Name=SUVH9)

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